TABLE 1.

Photophysical and Physiological Parameters Used in the Simulations

Symbol	Value
kp/kot*	11.9 μM
kos/koa[A]a	90 M−1
[S0] (t = 0)b	2.67 μM
Intercapillary distance	130 μm
Capillary radius	5.5 μm
Capillary length	350 μm
Initial blood velocityc	300 μm second−1
Γmet	11 μM second−1
SO2 (t = 0)	0.76
n	2.46

^*We used the value of k_p/k_ot measured from photofrin-PDT in multicell tumor spheroids [15].

The value of Γ_met was measured from multicell tumor spheroids (unpublished data).

^aGeorgakoudi and Foster [31].

^bStar et al. [32].

^cSchacht et al. [5].