Fig. 2.
Tukey box plots of the levels of IL-1β, IL-8, MMP-8 and GCF volume at “clinically healthy” sites (i.e. sites with pocket depth equal to 2 or 3 mm, no loss of attachment, no BOP, and no redness) in periodontally healthy and periodontitis subjects. The box indicates the lower and upper quartiles, the whiskers the 10th and 90th percentiles and the horizontal line in each box is the median. The circles indicate “outlier” values. The levels of each inflammatory mediator and the volume of GCF for this site category were averaged within a subject and then median determined across subjects in the 2 clinical groups separately. Significance of difference between the two groups was determined using the Mann-Whitney test. The numbers in parentheses represent the number of sites analyzed in each group.