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. 2009 Sep 1;587(Pt 23):5527–5540. doi: 10.1113/jphysiol.2009.179507

Figure 2. Changes induced upon decreasing physical activity from high to low levels.

Figure 2

A proposed exercise mimetic would have to prevent the same changes as natural exercise or the exercise pill would not be an authentic mimetic. Original drawing was generously made by Gheorghe Constantinescu.