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. Author manuscript; available in PMC: 2011 Jan 14.
Published in final edited form as: J Phys Chem B. 2010 Jan 14;114(1):626–632. doi: 10.1021/jp908944e

Figure 3.

Figure 3

(A) Mean-square fluctuation (MSF) of individual subunits of the closed-channel α4β2 nAChR in the control (black) and halothane (red) systems. The data were generated using the five slowest normal modes of the GNM analysis on the pentameric structure at the end of the 20-ns simulations. MSF was reduced in certain regions of the extracellular (EC) domain in the presence of halothane. (B) A snapshot of the α4-2 subunit with color-coded maxima (red and orange) and minima (blue) of the MSF shown in (A).