Skip to main content
. Author manuscript; available in PMC: 2011 Jan 14.
Published in final edited form as: J Phys Chem B. 2010 Jan 14;114(1):626–632. doi: 10.1021/jp908944e

Figure 4.

Figure 4

The non-bonded interaction energies between the β1–β2 loop (residues D47 to T57 in the α4 subunits and S44 to T54 in the β2 subunits) and the TM2–TM3 linker (S272 to L282 in the α4 subunits and S266 to L276 in the β2 subunits) of the closed- (left panels) and open-channel (right panels) α4β2 nAChR in the absence (black) or presence (red) of halothane over the course of 20-ns MD simulations. Both electrostatics and van der Waals were accounted for the non-bonded interaction. Note that a more negative value indicates a stronger non-bonded interaction.