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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Neuroimage. 2009 Mar 2;46(3):817–826. doi: 10.1016/j.neuroimage.2009.02.029

Table 4.

Regional brain activation correlation with MDMA use.

Regions of interest Percent BOLD signal change
 Percent activated voxels
(rs) p (rs) p
SMA L 0.517 0.058 0.343 0.230
SMA R 0.380 0.180 0.370 0.193
Precentral L 0.241 0.406 0.341 0.232
Precentral R 0.477 0.084 0.580 0.030
Caudate L 0.411 0.144 0.343 0.230
Caudate R 0.405 0.151 0.332 0.246
Putamen L 0.376 0.185 0.248 0.393
Putamen R 0.546 0.044 0.354 0.214
Pallidum L 0.453 0.104 0.280 0.333
Pallidum R 0.634 0.015 0.480 0.082
Thalamus L 0.418 0.137 0.575 0.032
Thalamus R 0.458 0.100 0.668 0.009
Postcentral L −0.034 0.908 0.262 0.365
Postcentral R 0.230 0.428 0.642 0.013

Correlation of percent BOLD signal change and percent activated voxels with lifetime episodes of MDMA use according to pre-defined anatomical region of interest for Tap 4 condition. rs = Spearman’s rho.

Bolded = statistically significant (p < 0.05; two-tailed).