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. Author manuscript; available in PMC: 2010 Nov 25.
Published in final edited form as: J Am Chem Soc. 2009 Nov 25;131(46):16720–16734. doi: 10.1021/ja9044357

Chart 1.

Chart 1

Ligand Optimization for the Coupling of 4-t-butylphenyl nonaflate and N-butyl acetamide.a

a ArONf (1 equiv), amide (2.5 equiv), [(allyl)PdCl]2 (1 mol%), ligand (5 mol%), base (2.0 equiv), 3 Å mol sieves (50 mg/ml), solvent (0.25 M), 110 °C, 18 h.