Table 4.
Reaction conditions: ArX (2.2 equiv), amide (1.0 equiv), [(allyl)PdCl]2 (1 mol%), JackiePhos (5 mol%), K3PO4 (3.0 equiv), 3 Å mol sieves (200 mg/mmol), toluene (0.25 M), 110 °C, 17 h.
Yields reported are an average of at least two runs determined to be >95% pure by elemental analysis or 1H NMR.
Runs conducted with [(allyl)PdCl]2 (1.5 mol%), JackiePhos (7 mol%), 42 h.