Table 1.
Clinical characteristics of men with diabetes at the time of radical prostatectomy stratified by race and obesity categories
| Diabetic at surgery | Not diabetic at surgery |
p value* | |
|---|---|---|---|
| No of patients (%) | 233 (19) | 1029 (82) | |
| Age in years at surgery | 0.82† | ||
| Mean ± SD | 61.6 ± 5.5 | 61.4 ± 6.5 | |
| Median (Range) | 62 (43 - 74) | 61 (43 - 86) | |
| Median year of surgery | 2003 | 2001 | <0.001† |
| PSA in ng/mL | |||
| Mean ± SD | 7.9 ± 6.1 | 9.5 ± 9.0 | 0.01† |
| Median (Range) | 6.2 (0.9 - 59.3) | 7.1 (0.1 - 140 ) | |
| Obesity in kg/m2 no (%) | <0.001 | ||
| Normal weight (<25) | 38 (16) | 280 (27) | |
| Overweight (25 to 29.9) | 92 (39) | 484 (47) | |
| Mildly obese (30 to 34.9) | 71 (30) | 196 (19) | |
| Moderately and Severely Obese (>35) | 32 (14) | 69 (7) | |
| Race no (%) | 0.003 | ||
| White | 103 (44) | 567 (55) | |
| Black | 130 (56) | 462 (45) | |
| Biopsy Gleason Score no (%) | 0.07 | ||
| 2-6 | 128 (55) | 650 (63) | |
| 7 | 61 (26) | 220 (21) | |
| 8-10 | 44 (19) | 159 (16) | |
| Clinical Stage no (%) | 0.4 | ||
| T1 | 137 (59) | 573 (56) | |
| T2 and above | 96 (41) | 456 (44) | |
| Pathological Gleason Score no (%) | <0.001 | ||
| 2-6 | 59 (26) | 416(41) | |
| 3+4 | 111 (48) | 400 (39) | |
| ≥4+3 | 61 (26) | 205 (20) | |
| ECE no (%) | 51 (22) | 194 (19) | 0.3 |
| SVI no (%) | 29 (13) | 88 (9) | 0.07 |
| PSM no (%) | 110 (48) | 447 (44) | 0.3 |
| LNI no (%) | 3 (34) | 17 (26) | 0.04 |
ECE – extracapsular extension, PSM – positive surgical margins SVI – seminal vesicle invasion LNI – lymph node involvement
*
p value assessed by chi squared test unless otherwise specified
†
p value assessed by rank sum test