Table 4.
No. Patients | Mean adjusted PSADT † (95% CI) | p | p – interaction by race†† |
P – interaction by obesity‡ |
|||
---|---|---|---|---|---|---|---|
Total | Diabetic | Diabetic at surgery |
Not diabetic at surgery |
||||
Overall | 192 | 33 | 23.4 (15.7 - 34.8) | 16.7 (13.0 - 21.4) | 0.12 | 0.11 | |
White | 99 | 15 | 16.4 (8.8 - 30.3) | 18.7 (12.8 - 27.3) | 0.71 | 0.75 | |
Non obese | 69 | 5 | 20.6 (7.4 - 57.5) | 19.8 (12.7 - 30.9) | 0.94 | ||
Obese | 30 | 10 | 11.0 (4.8 - 25.0) | 22.7 (9.6 - 53.7) | 0.24 | ||
Black | 93 | 18 | 29.3 (17.0 - 50.5) | 14.9 (10.6 - 21.0) | 0.02 | 0.87 | |
Non obese | 61 | 11 | 42.5 (20.3 - 89.0) | 21.6 (13.7 - 34.1) | 0.06 | ||
Obese | 32 | 7 | 27.5 (11.3 - 67.1) | 9.6 (6.0 - 15.3) | 0.02 |
Using log transformed PSA doubling time as a continuous variable in a linear regression model
Obesity was defined as a BMI ≥ 30 kg/m2
Adjusted for age, year of surgery, race, BMI, clinical stage, biopsy Gleason score, center, and pre-operative PSA
p – interaction by race assessed by including the cross product term between diabetes and race in the model
p – interaction by obesity assessed by including the cross product term between obesity and race in the model