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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Jan;19(1):9–17. doi: 10.1158/1055-9965.EPI-09-0777

Table 4.

Mean adjusted estimates and 95% CI of PSADT* after recurrence among men with diabetes at surgery stratified by race and obesity**

No. Patients Mean adjusted PSADT (95% CI) p p –
interaction by race††
P –
interaction by obesity

Total Diabetic Diabetic at
surgery
Not diabetic at
surgery
Overall 192 33 23.4 (15.7 - 34.8) 16.7 (13.0 - 21.4) 0.12 0.11
White 99 15 16.4 (8.8 - 30.3) 18.7 (12.8 - 27.3) 0.71 0.75
 Non obese 69 5 20.6 (7.4 - 57.5) 19.8 (12.7 - 30.9) 0.94
 Obese 30 10 11.0 (4.8 - 25.0) 22.7 (9.6 - 53.7) 0.24
Black 93 18 29.3 (17.0 - 50.5) 14.9 (10.6 - 21.0) 0.02 0.87
 Non obese 61 11 42.5 (20.3 - 89.0) 21.6 (13.7 - 34.1) 0.06
 Obese 32 7 27.5 (11.3 - 67.1) 9.6 (6.0 - 15.3) 0.02
*

Using log transformed PSA doubling time as a continuous variable in a linear regression model

**

Obesity was defined as a BMI ≥ 30 kg/m2

Adjusted for age, year of surgery, race, BMI, clinical stage, biopsy Gleason score, center, and pre-operative PSA

††

p – interaction by race assessed by including the cross product term between diabetes and race in the model

p – interaction by obesity assessed by including the cross product term between obesity and race in the model