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. 2009;11(6):353–356. doi: 10.4088/PCC.09r00853

Table 3.

Sternbach's and Boyer's Criteria for Serotonin Syndrome

Sternbach's Criteria2 Boyer's Criteria3
At least 3 of the following required: Any 1 of the following required:
 Mental status changes Tremor and hyperreflexia
 Agitation Spontaneous clonus
 Myoclonus Muscle rigidity, temperature > 38°C, and ocular or inducible clonus
 Hyperreflexia
 Diaphoresis
 Shivering Ocular clonus and diaphoresis or agitation
 Tremor
 Diarrhea Inducible clonus and diaphoresis or agitation
 Incoordination
 Fever