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. Author manuscript; available in PMC: 2010 Jan 12.
Published in final edited form as: Eur J Neurosci. 2008 Dec;28(11):2278–2287. doi: 10.1111/j.1460-9568.2008.06524.x

Fig. 1.

Fig. 1

Effects of voluntary exercise on the mRNA levels of AMPK (A), uMtCK (B), UCP-2 (C), ghrelin (D) and IGF-I (E) in the hippocampus. Exercise (Ex/Con) elevated the expression of these metabolism-related molecules relative to sedentary animals (Sed/Con). The injection of the BDNF inhibitor TrkB-IgG into the hippocampus abolished these increases in exercise rats (Ex/IgG). Levels of AMPK, uMtCK and UCP-2 are expressed as a percent of sedentary controls (Sed/Con). Each value represents the mean ± SEM (two-way anova, *P < 0.05, **P < 0.01). Sed/IgG, sedentary with TrkB-IgG injection.