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A significant positive correlation was found between running distance (Avg Km/day) and CAMKII expression in the Exc group (Excise; r = 0.82, n=6, p < 0.05). Administration of the CAMKII blocker disrupted this positive association and resulted in a negative correlation between running distance and CAMKII expression (Exercise/KN; r = −0.78, n=8, p < 0.05) in individual animals. The association is illustrated by the computer generated best-fit line.
