Figure 1.

PML-RARα specific PCR–M) marker, lane 1) before ATO treatment, lane 2) G-CSF mobilized stem cells, lane 3) G-CSF + AMD3100 mobilized stem cells. Lanes were processed to secure clearness since other patient samples were performed routinely in parallel. Graph: treatment course after relapse. Local irradiation with 30 Gy starting December 2005 and 20 Gy starting in April 2006. Black arrows indicate intrathecal application of liposomal cytarabine. White arrows pointing upward indicate apheresis #1 with G-CSF and apheresis #2 with G-CSF and AMD3100. White arrow pointing downward indicates autologous SCT after myeloablative conditioning with 12 Gy TBI and intravenous cyclophosphamide.