Fig. 5. L90V but not the F52dup ODDD mutation disrupts basolateral targeting of Cx43-eYFP in MDCK cells.
A, B. Z sections of MDCK monolayers expressing the F52dup mutant construct showed that this mutation does not affect basolateral targeting of Cx43-eYFP (2 independent clones). C, D. Z sections of MDCK monolayers expressing the L90V mutant construct showed that basolateral targeting of Cx43-eYFP was disrupted (2 independent clones). Scale bar, 10 um.