FIGURE 4.
Cα RMSD values between representative ACP structures. Disulfide-linked PfACP is labeled “oxACP”, and reduced PfACP is labeled “redACP.” PfACP crystal structures have RMSD values of 0.5–0.6 Å when compared to each other, and slightly higher values (0.6–0.8 Å) when compared to other parasite and bacterial crystal structures of both holo and acylated forms. NMR structures of either holo or acylated ACP have significantly larger RMSD values when compared to the PfACP crystal structures. See supplementary Fig. S2 for a more complete listing of ACP structures.