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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Dev Dyn. 2009 Feb;238(2):431–442. doi: 10.1002/dvdy.21854

Fig.2. Cushion morphology in Tgfb1−/−, Tgfb2−/− and Tgfb3−/− mice at E14.5.

Fig.2

A-D: Representative of serially sectioned H-E stained images of wild-type (A), Tgfb1−/− (B), Tgfb2−/− (C) and Tgfb3−/− (D). Only Tgfb2−/− mice develop dysplastic or enlarged cushions (C, arrows) (see Results section for a quantification of total cushion cells). Notably, this mutant heart also has overriding tricuspid valves. Scale bar: 200 µm (A–D). TV, tricuspid valves; MV, mitral valves; RA, right atrium; RV, right ventricle; LV, left ventricle.