Table 3.
Genes in more than one study. Abbreviations: IER = Ihara epileptic rat; MA = microarray; SAGE = serial analysis of gene expression.
| Gene name | Abbreviation | Reports | Platform | Conflicting | Epilepsy model | ||||
|---|---|---|---|---|---|---|---|---|---|
| SAGE | MA | Electrical kindling | Chemical kindling | Human | IER | ||||
| 14‐3‐3 protein gamma | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 | |
| Actin related protein 2/3 complex | Arpc | 3 | 1 | 2 | No | 1 | 2 | 0 | 0 |
| α‐tubulin | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 | |
| Brain derived neurotrophic factor | BDNF | 4 | 1 | 3 | No | 2 | 2 | 0 | 0 |
| Calponin 3, acidic | Cnn3 | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 |
| Cathepsin D | Ctsd | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 |
| Cathepsin S | Ctss | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 |
| Cholecystokinin | CCK | 3 | 1 | 2 | No | 1 | 0 | 2 | 0 |
| Chromogranin B | Chgb | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 |
| Clone BB.1.4.1 | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 | |
| Complexin 2 | Cplx2 | 2 | 2 | 0 | No | 1 | 0 | 1 | 0 |
| Cystatin C | Cst3 | 4 | 2 | 2 | No | 2 | 2 | 0 | 0 |
| Ectodermal neural cortex | Enc1 | 2 | 1 | 1 | No | 0 | 0 | 2 | 0 |
| Elongation factor‐1α | Efa1 | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 |
| Epithelin 1 and 2 | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 | |
| ESTs, Hs to MBD3 | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 | |
| Ferritin heavy chain | Fth | 3 | 2 | 1 | No | 2 | 1 | 0 | 0 |
| Glial fibrillary acidic protein | GFAP | 5 | 2 | 3 | No | 1 | 3 | 1 | 0 |
| Granulin | Grn | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 |
| Growth factor receptor bound protein 2 | Grb2 | 2 | 0 | 2 | No | 0 | 1 | 1 | 0 |
| Heat shock protein 27 | Hsp27 | 2 | 0 | 2 | No | 0 | 2 | 0 | 0 |
| Heat shock protein 70 | Hsp70 | 4 | 1 | 3 | No | 1 | 2 | 1 | 0 |
| Metallothionein 2 | Mt2 | 3 | 0 | 3 | No | 0 | 3 | 0 | 0 |
| Metallothionein 3 | Mt3 | 2 | 2 | 0 | No | 1 | 0 | 1 | 0 |
| MHC class Ib antigen | 2 | 0 | 2 | No | 0 | 2 | 0 | 0 | |
| Myelin basic protein | Mbp | 3 | 2 | 1 | No | 1 | 1 | 1 | 0 |
| NDRG family member 2 | NDRG2 | 2 | 1 | 1 | No | 0 | 0 | 2 | 0 |
| Neural precursor expressed, developmentally downregulated gene | Nedd | 2 | 2 | 0 | No | 1 | 0 | 1 | 0 |
| p41‐Arc | arpD | 2 | 0 | 2 | No | 0 | 2 | 0 | 0 |
| Pleckstrin | Pscd1 | 3 | 2 | 1 | No | 1 | 0 | 2 | 0 |
| Preprocathepsin | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 | |
| Protein p9Ka homologous to calcium‐binding protein (S100) | S100 | 5 | 1 | 4 | No | 2 | 3 | 0 | 0 |
| Secreted protein, acidic, cysteine‐rich (osteonectin) | SPARC | 4 | 2 | 2 | No | 1 | 2 | 1 | 0 |
| Spinophilin | Spn | 2 | 1 | 1 | No | 1 | 1 | 0 | 0 |
| Tachykinin 1 | Tac1 | 2 | 0 | 2 | No | 0 | 2 | 0 | 0 |
| Thyrotropin releasing hormone | TRH | 4 | 0 | 4 | No | 1 | 3 | 0 | 0 |
| Tissue inhibitor of metalloproteinase 1 | Timp1 | 3 | 0 | 3 | No | 1 | 2 | 0 | 0 |
| Transferrin | Tsf | 2 | 0 | 2 | No | 0 | 1 | 1 | 0 |
| Vimentin | Vim | 2 | 0 | 2 | No | 0 | 2 | 0 | 0 |
| Apolipoprotein | ApoE | 4 | 3 | 1 | Yes | 3 | 0 | 1 | 0 |
| Ca(2+)/calmodulin‐dependent protein kinase II | CaMKII | 4 | 1 | 3 | Yes | 2 | 1 | 1 | 0 |
| Cabonic anhydrase | CA | 2 | 1 | 1 | Yes | 0 | 0 | 2 | 0 |
| CD 99 antigen | CD99 | 2 | 1 | 1 | Yes | 0 | 0 | 1 | 1 |
| Glyceraldehyde phosphate dehydrogenaase | GAPDH | 3 | 2 | 1 | Yes | 2 | 1 | 0 | 0 |
| Glycoprotein 65 | 2 | 1 | 1 | Yes | 1 | 1 | 0 | 0 | |
| Growth arrest and DNA damage‐inducible protein 45 | GADD45 | 3 | 0 | 3 | Yes | 0 | 3 | 0 | 0 |
| Laminin receptor 1 | Lamr1 | 2 | 1 | 1 | Yes | 0 | 1 | 1 | 0 |
| Metallothionein 1 | Mt1 | 3 | 1 | 2 | Yes | 1 | 2 | 0 | |
| Ornithine decarboxylase | Oda | 2 | 1 | 1 | Yes | 0 | 1 | 1 | 0 |
| Peptidylprolyl isomerase B (cyclophilin B) | Ppib | 2 | 0 | 2 | Yes | 0 | 2 | 0 | 0 |
| Platelet activation factor acetylhydrolase | Pafah | 3 | 1 | 2 | Yes | 0 | 2 | 1 | 0 |
| Protein kinase C β | PrkCB | 2 | 0 | 2 | Yes | 0 | 2 | 0 | |
| Proteolipid protein 1 | Plp | 2 | 1 | 1 | Yes | 1 | 0 | 1 | 0 |
| Thymosin beta | Tmbx | 4 | 3 | 1 | Yes | 2 | 1 | 1 | 0 |
| Serum/glucocorticoid regulated kinase | Sgk | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| CD 14 antigen | CD14 | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| CD 74 antigen | CD74 | 2 | 0 | 2 | Unknown | 1 | 0 | 1 | 0 |
| Corticotropin releasing hormone | CRH | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| GABA(A) receptor associated protein | GABARAP | 2 | 1 | 1 | Unknown | 1 | 0 | 0 | 1 |
| Galanin | Gal | 3 | 0 | 3 | Unknown | 1 | 2 | 0 | 0 |
| Glutamate receptor, ionotropic, N‐methyl D‐aspartate 2A | Grin2A | 2 | 0 | 2 | Unknown | 1 | 0 | 1 | 0 |
| Homer homolog 1 | Homer | 3 | DD, MPSS | 1 | Unknown | 3 | 0 | 0 | 0 |
| Neuritin | Nrn | 2 | 0 | 2 | Unknown | 0 | 2 | 0 | 0 |
| Neuropeptide Y | Npy | 4 | 0 | 4 | Unknown | 1 | 3 | 0 | 0 |
| Nuclear factor of kappa light chain gene enhancer in B‐cells inhibitor, alpha | Nfkbia | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| Peptidylglycin‐alpha‐amidating monooxygenase | PAM | 2 | 0 | 2 | Unknown | 0 | 2 | 0 | 0 |
| Prostaglandin‐endoperoxide synthase 2 | Ptgs2 | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| Secreted phosphoprotein 1 | Spp1 | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| Signal transducer and activator of transcription 3 | Stat3 | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| Somatostatin | Sst | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| Synaptophysin | Syp | 2 | 0 | 2 | Unknown | 2 | 0 | 0 | 0 |
| Syndecan 4 | Sdc4 | 2 | 0 | 2 | Unknown | 1 | 1 | 0 | 0 |
| VGF nerve growth factor inducible | Vgf | 3 | 0 | 3 | Unknown | 1 | 2 | 0 | 0 |
| β2‐microglobulin | β2m | 2 | 0 | 2 | Unknown | 2 | 0 | 0 | 0 |