Table 3.

Proportion of cases confirmed, by disease group, and number of validations in each disease category, by validation method

	Internal		External
			Request additional information from GP
Disease group	Manual review or diagnostic algorithm	Sensitivity analysis	Questionnaire to GP only	Questionnaire and record request to GP	Record request to GP only	Comparison of rates	Total	Median (range) proportion of cases confirmed†
Infectious and parasitic	0	1	1	0	0	15	17	93.00	(n/a)
Neoplasms	7	0	5	2	5	7	26	95.25	(74–100)
Blood and blood-forming organs	0	0	0	1	3	1	5	57.61	(31–89)
Endocrine, nutritional and metabolic	4	0	0	5	1	7	17	87.70	(53–100)
Mental and behavioural disorders	1	0	1	5‡	8	10	20	83.00	(52–100)
Nervous system	1	4	1	1	6	12	25	81.00	(39–100)
Eye and adnexa	0	0	0	2	3	3	8	89.47	(75–97)
Ear and mastoid process	0	0	0	0	0	2	2	n/a
Circulatory system	10	3	7‡	10	20	12	55	85.30	(48–100)
Respiratory system	2	0	3	2	2	25	34	88.00	(26–100)
Digestive system	1	6‡	13	1	19	12	46	87.35	(24–100)
Skin and subcutaneous tissue	1	1	5	1	0	5	13	94.55	(82–100)
Musculoskeletal system and connective tissue	2	6‡	2	1	4	10	19	80.00	(33–97)
Genitourinary system	0	1	0	4	1	1	7	91.00	(28–100)
Pregnancy, childbirth and the puerperium	0	0	0	0	0	0	0	n/a
Perinatal period	0	0	0	0	0	0	0	n/a
Congenital	0	0	3‡	0	0	2	2	93.50	(71–100)
Injury and poisoning	1	1	2	2	3	3	12	89.52	(73–100)
External causes of morbidity and mortality	0	0	0	1	0	8	9	100.00	(n/a)
Other*	1	0	0	1	3‡	8	10	90.00	(45–100)
Total	31	11	33	34	75	143	327	88.6	(24–100)

^*Includes multiple disease groups, ill-defined conditions, miscellaneous, stillbirth and mortality.

^†Based on GP record request, algorithm and manual review.

^‡Investigated the validity of a composite outcome combining more than one diagnosis.