Table 2.
The pattern of the frequency of the rearrangements detected in Ig/TCR loci in Polish B-cell precursor ALL patients
| Number of patients | Frequency of rearrangements | |||||
|---|---|---|---|---|---|---|
| subjected to PCR screening | with at least one rearrangement detected | |||||
| Ig | IGH | VH-(DH)-JH | 58 | 43 | 74% | |
| DH-JH | 23 | 2 | 9% | |||
| total IGH | 58a, 23b | 43a, 19b | 74%a, 83%b | |||
| IGK-Kde | Vκ-Kde | 58 | 18 | 31% | ||
| Intron-Kde | 58 | 9 | 16% | |||
| total IGK-Kde | 58 | 24 | 41% | |||
| Total Ig | 58a, 23b | 49a, 21b | 84%a, 91%b | |||
| TCR | TCRD | incomplete | Vδ2-Dδ3 | 58 | 26 | 45% |
| Dδ2-Dδ3 | 58 | 12 | 21% | |||
| total inc. TCRD | 58 | 32 | 55% | |||
| Vδ2-Jα | Vδ2-(Dδ3)-Jα29 | 58 | 8 | 14% | ||
| Vδ2-(Dδ3)-Jα | 23 | 5 | 22% | |||
| total Vδ2-Jα | 58a, 23b | 13a, 8b | 22%a, 35%b | |||
| Total TCRD | 58a, 23b | 38a, 18b | 66%a, 78%b | |||
| TCRG | Vγ-Jγ | 58 | 29 | 50% | ||
| TCRB | Vβ-(Dβ)-Jβ | 23 | 2 | 9% | ||
| Dβ-Jβ | 23 | 1 | 4% | |||
| total TCRB | 23 | 3 | 13% | |||
| Total TCR | 58a, 23b | 47a, 20b | 81%a, 87%b | |||
| Total Ig/TCR | 58a, 23b | 56a, 23b | 97%a, 100%b | |||
a, b Refer to groups of patients in whom particular rearrangements were screened for in either the singleplex or the combined singleplex-multiplex PCR approach.