Table 3.
Life span data for baculovirus p35 experiments, with means, standard deviations, medians, percent change in mean and median, and log rank p value.
| CrossMxF | RU486 | Genotype | Sex | N | Meana | Median | %Change in Mean | %Change in Median | Log Rank p Value |
| Exp1 Life span assay of three UAS-p35 lines and UAS-p53.259H with GS255B driver at 25C | |||||||||
| 7-1 | - | w/Y; 255B/+; + | M | 120 | 84.6±14.25 | 90 | --------- | --------- | --------- |
| A | w/Y; 255B/+; + | M | 119 | 83.08±10.94 | 86 | -1.8 | -4.44 | 0.014 | |
| L | w/Y; 255B/+; + | M | 123 | 78.44±22.48 | 86 | -7.28 | -4.44 | 0.244 | |
| - | w/+; 255B/+; + | F | 116 | 92.02±9.64 | 94 | --------- | --------- | --------- | |
| A | w/+; 255B/+; + | F | 121 | 94.69±8.61 | 94 | 2.9 | 0 | 0.009 | |
| L | w/+; 255B/+; + | F | 124 | 91.97±15.74 | 94 | -0.05 | 0 | 0.047 | |
| 1-9 | - | p35,w*/Y; 255B/+; + | M | 120 | 68.93±12.49 | 70 | --------- | --------- | --------- |
| A | p35,w*/Y; 255B/+; + | M | 123 | 68.62±11.76 | 70 | -0.45 | 0 | 0.681 | |
| L | p35,w*/Y; 255B/+; + | M | 98 | 33.1±22.91 | 26 | -51.98 | -62.86 | 0 | |
| - | p35,w*/+; 255B/+; + | F | 122 | 83.28±15.13 | 86 | --------- | --------- | --------- | |
| A | p35,w*/+; 255B/+; + | F | 130 | 77.15±20.92 | 82 | -7.36 | -4.65 | 0.11 | |
| L | p35,w*/+; 255B/+; + | F | 125 | 57.52±35.8 | 70 | -30.93 | -18.6 | 0.001 | |
| 10-1 | - | w/Y; 255B/p35; + | M | 117 | 54.48±13 | 54 | --------- | --------- | --------- |
| A | w/Y; 255B/p35; + | M | 121 | 57.26±8.45 | 58 | 5.1 | 7.41 | 0.583 | |
| L | w/Y; 255B/p35; + | M | 110 | 34.25±19.5 | 34 | -37.13 | -37.04 | 5.60E-10 | |
| - | w/w*; 255B/p35; + | F | 120 | 64.05±14.63 | 66 | --------- | --------- | --------- | |
| A | w/w*; 255B/p35; + | F | 126 | 60.79±16.68 | 66 | -5.09 | 0 | 0.188 | |
| L | w/w*; 255B/p35; + | F | 123 | 49.37±32.2 | 54 | -22.92 | -18.18 | 0.436 | |
| 11-1 | - | w/Y; 255B/+; p35/+ | M | 133 | 86.03±12.51 | 90 | --------- | --------- | --------- |
| A | w/Y; 255B/+; p35/+ | M | 122 | 81.31±13.87 | 84 | -5.49 | -6.67 | 8.92E-06 | |
| L | w/Y; 255B/+; p35/+ | M | 56 | 46.18±24.21 | 44 | -46.32 | -51.11 | 0 | |
| - | w/w*; 255B/+; p35/+ | F | 126 | 87.54±10.04 | 90 | --------- | --------- | --------- | |
| A | w/w*; 255B/+; p35/+ | F | 127 | 82.19±9.91 | 82 | -6.11 | -8.89 | 8.60E-05 | |
| L | w/w*; 255B/+; p35/+ | F | 126 | 64.63±29.62 | 75 | -26.17 | -16.67 | 4.67E-07 | |
| 29-1 | - | w/Y; 255B/+;p53.259H/+ | M | 118 | 71.54±13.86 | 72 | --------- | --------- | --------- |
| A | w/Y; 255B/+;p53.259H/+ | M | 125 | 68.90±10.41 | 70 | -3.70 | -2.78 | 0.002 | |
| L | w/Y; 255B/+;p53.259H/+ | M | 119 | 67.73±16.92 | 70 | -5.33 | -2.78 | 0.069 | |
| - | w; 255B/+; p53.259H/+ | F | 119 | 75.40±8.50 | 76 | --------- | --------- | --------- | |
| A | w; 255B/+; p53.259H/+ | F | 119 | 80.66±10.98 | 82 | 6.98 | 7.89 | 4.05E-08 | |
| L | w; 255B/+; p53.259H/+ | F | 125 | 70.24±22.02 | 76 | -6.84 | 0 | 0.202 | |
| Exp2 Life span assay of three UAS-p35 lines with head FB driver, whole body FB driver and GS255A driver at 25C | |||||||||
| 3-7 | - | +/Y; S32/+; + | M | 75 | 59.23±14.11 | 64 | --------- | --------- | --------- |
| A | +/Y; S32/+; + | M | 63 | 55.21±15.74 | 60 | -6.79 | -6.25 | 0.013 | |
| - | w/+; S32/+; + | F | 111 | 59.91±18.96 | 60 | --------- | --------- | --------- | |
| A | w/+; S32/+; + | F | 115 | 63.77±17.71 | 66 | 6.45 | 10 | 0.263 | |
| 3-9 | - | p35,w*/Y; S32/+; + | M | 122 | 62.69±10.62 | 64 | --------- | --------- | --------- |
| A | p35,w*/Y; S32/+; + | M | 105 | 58.3±13.45 | 60 | -6.99 | -6.25 | 0.022 | |
| - | p35,w*/w; S32/+; + | F | 112 | 59.95±25 | 72 | --------- | --------- | --------- | |
| A | p35,w*/w; S32/+; + | F | 108 | 59±24.86 | 68 | -1.58 | -5.56 | 0.974 | |
| 3-10 | - | w*/Y; S32/p35; + | M | 123 | 45.19±7.61 | 46 | --------- | --------- | --------- |
| A | w*/Y; S32/p35; + | M | 120 | 41.52±6.84 | 42 | -8.12 | -8.7 | 1.96E-04 | |
| - | w*/w; S32/p35; + | F | 121 | 61.62±8.71 | 62 | --------- | --------- | --------- | |
| A | w*/w; S32/p35; + | F | 105 | 63.28±10.6 | 66 | 2.69 | 6.45 | 0.036 | |
| 3-11 | - | w*/Y; S32/+; p35/+ | M | 125 | 62.67±12.41 | 64 | --------- | --------- | --------- |
| A | w*/Y; S32/+; p35/+ | M | 125 | 60.78±14.07 | 62 | -3.03 | -3.13 | 0.174 | |
| - | w*/w; S32/+; p35/+ | F | 109 | 68.44±17.09 | 74 | --------- | --------- | --------- | |
| A | w*/w; S32/+; p35/+ | F | 113 | 70.52±18.12 | 76 | 3.04 | 2.7 | 0.043 | |
| 4-7 | - | +/Y; S106 S32/+; + | M | 116 | 54.12±9.89 | 56 | --------- | --------- | --------- |
| A | +/Y; S106 S32/+; + | M | 118 | 52.68±9.77 | 52 | -2.67 | -7.14 | 0.208 | |
| - | w/+; S106 S32/+; + | F | 110 | 58.82±14.95 | 62 | --------- | --------- | --------- | |
| A | w/+; S106 S32/+; + | F | 120 | 58.07±16.45 | 63 | -1.28 | 1.61 | 0.569 | |
| 4-9 | - | p35,w*/Y; S106 S32/+; + | M | 121 | 47.21±8.48 | 46 | --------- | --------- | --------- |
| A | p35,w*/Y; S106 S32/+; + | M | 110 | 47.67±10.28 | 48 | 0.99 | 4.35 | 0.263 | |
| - | p35,w*/w; S106 S32/+; + | F | 119 | 55.18±22.95 | 66 | --------- | --------- | --------- | |
| A | p35,w*/w; S106 S32/+; + | F | 126 | 47.79±24.9 | 62 | -13.38 | -6.06 | 0.01 | |
| 4-10 | - | w*/Y; S106 S32/p35; + | M | 125 | 33.39±4.44 | 34 | --------- | --------- | --------- |
| A | w*/Y; S106 S32/p35; + | M | 125 | 32.3±6.16 | 32 | -3.26 | -5.88 | 0.475 | |
| - | w*/w; S106 S32/p35; + | F | 121 | 49.55±8.14 | 50 | --------- | --------- | --------- | |
| A | w*/w; S106 S32/p35; + | F | 121 | 50.84±8.85 | 50 | 2.6 | 0 | 0.107 | |
| 4-11 | - | w*/Y; S106 S32/+; p35/+ | M | 125 | 47.15±6.81 | 48 | --------- | --------- | --------- |
| A | w*/Y; S106 S32/+; p35/+ | M | 117 | 48.6±8.42 | 48 | 3.07 | 0 | 0.072 | |
| - | w*/w; S106 S32/+; p35/+ | F | 125 | 56.81±13.02 | 60 | --------- | --------- | --------- | |
| A | w*/w; S106 S32/+; p35/+ | F | 116 | 60.69±11.7 | 64 | 6.83 | 6.67 | 0.004 | |
| 2-7 | - | +/Y; 255A/+; + | M | 114 | 66.04±8.95 | 67 | --------- | --------- | --------- |
| A | +/Y; 255A/+; + | M | 117 | 58.97±15.36 | 62 | -10.69 | -7.46 | 1.48E-05 | |
| - | w/+; 255A/+; + | F | 114 | 72.65±13.95 | 78 | --------- | --------- | --------- | |
| A | w/+; 255A/+; + | F | 116 | 75.02±13.19 | 78 | 3.26 | 0 | 0.064 | |
| 2-9 | - | p35,w*/Y; 255A/+; + | M | 111 | 65.98±14.65 | 66 | --------- | --------- | --------- |
| A | p35,w*/Y; 255A/+; + | M | 115 | 59.82±13.31 | 60 | -9.34 | -9.09 | 3.78E-05 | |
| - | p35,w*/w; 255A/+; + | F | 113 | 58.95±20.26 | 64 | --------- | --------- | --------- | |
| A | p35,w*/w; 255A/+; + | F | 117 | 69.21±17.4 | 72 | 17.4 | 12.5 | 1.32E-06 | |
| 2-10 | - | w*/Y;255A/p35; + | M | 113 | 48.98±9.74 | 48 | --------- | --------- | --------- |
| A | w*/Y;255A/p35; + | M | 125 | 47.66±7.19 | 48 | -2.69 | 0 | 0.03 | |
| - | w*/w; 255A/p35; + | F | 115 | 60.57±16.71 | 66 | --------- | --------- | --------- | |
| A | w*/w; 255A/p35; + | F | 118 | 62±17.79 | 70 | 2.35 | 6.06 | 0.052 | |
| 2-11 | - | w*/Y; 255A/+; p35/+ | M | 115 | 63.66±11.4 | 64 | --------- | --------- | --------- |
| A | w*/Y; 255A/+; p35/+ | M | 114 | 64.92±9.41 | 64 | 1.98 | 0 | 0.776 | |
| - | w*/w; 255A/+; p35/+ | F | 120 | 67.05±11.58 | 70 | --------- | --------- | --------- | |
| A | w*/w; 255A/+; p35/+ | F | 120 | 68.75±9.08 | 70 | 2.54 | 0 | 0.41 | |
| Exp3 Life span assay of two UAS-p35 lines with whole body FB driver at 29C | |||||||||
| 7-4 | - | w/Y; S106 S32/+; + | M | 124 | 49.15±12.5 | 54 | --------- | --------- | --------- |
| L | w/Y; S106 S32/+; + | M | 121 | 49.11±10.75 | 52 | -0.08 | -3.7 | 0.655 | |
| - | w/+; S106 S32/+; + | F | 121 | 51.95±10.82 | 54 | --------- | --------- | --------- | |
| L | w/+; S106 S32/+; + | F | 118 | 55.29±10.06 | 60 | 6.42 | 11.11 | 0.029 | |
| 8-4 | - | w/Y; S106 S32/+; + | M | 121 | 47.16±10.27 | 48 | --------- | --------- | --------- |
| L | w/Y; S106 S32/+; + | M | 118 | 42.85±12.89 | 44 | -9.14 | -8.33 | 0.002 | |
| - | w/w; S106 S32/+; + | F | 124 | 50.48±11.91 | 56 | --------- | --------- | --------- | |
| L | w/w; S106 S32/+; + | F | 125 | 51.63±8.47 | 54 | 2.27 | -3.57 | 0.196 | |
| 10-4 | - | w/Y; S106 S32/p35; + | M | 121 | 50.43±6.73 | 52 | --------- | --------- | --------- |
| L | w/Y; S106 S32/p35; + | M | 121 | 46.5±8.28 | 48 | -7.8 | -7.69 | 4.23E-05 | |
| - | w*/w; S106 S32/p35; + | F | 120 | 50.4±12.84 | 56 | --------- | --------- | --------- | |
| L | w*/w; S106 S32/p35; + | F | 129 | 48.57±8.9 | 50 | -3.62 | -10.71 | 1.45E-05 | |
| 11-4 | - | w/Y; S106 S32/+; p35/+ | M | 126 | 44.03±6.5 | 46 | --------- | --------- | --------- |
| L | w/Y; S106 S32/+; p35/+ | M | 122 | 41.92±10.42 | 46 | -4.8 | 0 | 0.208 | |
| - | w*/w; S106 S32/+; p35/+ | F | 122 | 58.03±6.59 | 60 | --------- | --------- | --------- | |
| L | w*/w; S106 S32/+; p35/+ | F | 124 | 54.81±8.05 | 56 | -5.56 | -6.67 | 8.84E-07 | |
| Exp4 Life span assay of two UAS-p35 lines with Elav driver at 29C | |||||||||
| 7-5 | - | yw/Y; +/+; Elav/+ | M | 131 | 53.92±7.15 | 54 | --------- | --------- | --------- |
| A | yw/Y; +/+; Elav/+ | M | 129 | 52.33±8.14 | 53 | -2.95 | -1.85 | 0.083 | |
| L | yw/Y; +/+; Elav/+ | M | 59 | 35.85±10.58 | 38 | -33.51 | -29.63 | 0 | |
| - | yw/+; +/+; Elav/+ | F | 127 | 58.15±7.22 | 60 | --------- | --------- | --------- | |
| A | yw/+; +/+; Elav/+ | F | 129 | 57.11±5.19 | 58 | -1.79 | -3.33 | 0.013 | |
| L | yw/+; +/+; Elav/+ | F | 120 | 43.46±7.94 | 44 | -25.26 | -26.67 | 0 | |
| 8-5 | - | yw/Y; +/+; Elav/+ | M | 126 | 44.08±8.36 | 44.5 | --------- | --------- | --------- |
| A | yw/Y; +/+; Elav/+ | M | 120 | 43.32±8.76 | 45 | -1.73 | 1.12 | 0.186 | |
| L | yw/Y; +/+; Elav/+ | M | 102 | 26.24±8.51 | 26 | -40.48 | -41.57 | 0 | |
| - | yw/w; +/+; Elav/+ | F | 124 | 46.88±9.92 | 50 | --------- | --------- | --------- | |
| A | yw/w; +/+; Elav/+ | F | 124 | 48.13±7.5 | 49.5 | 2.67 | -1 | 0.406 | |
| L | yw/w; +/+; Elav/+ | F | 114 | 34.82±10.34 | 36 | -25.73 | -28 | 0 | |
| 10-5 | - | yw/Y; p35/+; Elav/+ | M | 125 | 42.34±6.38 | 44 | --------- | --------- | --------- |
| A | yw/Y; p35/+; Elav/+ | M | 122 | 43.34±10.34 | 46 | 2.38 | 4.55 | 0.007 | |
| L | yw/Y; p35/+; Elav/+ | M | 9 | 20.89±10.3 | 26 | -50.66 | -40.91 | 0 | |
| - | yw/w*; p35/+; Elav/+ | F | 121 | 49±10.63 | 52 | --------- | --------- | --------- | |
| A | yw/w*; p35/+; Elav/+ | F | 126 | 50.16±6.4 | 51 | 2.36 | -1.92 | 0.014 | |
| L | yw/w*; p35/+; Elav/+ | F | 9 | 28.22±10.27 | 32 | -42.4 | -38.46 | 1.60E-14 | |
| 11-5 | - | yw/Y; +; Elav/p35 | M | 120 | 51.24±10.46 | 54 | --------- | --------- | --------- |
| A | yw/Y; +; Elav/p35 | M | 121 | 48.62±10.1 | 52 | -5.12 | -3.7 | 1.22E-06 | |
| L | yw/Y; +; Elav/p35 | M | 1 | 10±NA | 10 | -80.48 | -81.48 | 5.60E-10 | |
| - | yw/w*; +; Elav/p35 | F | 118 | 56.77±3.89 | 58 | --------- | --------- | --------- | |
| A | yw/w*; +; Elav/p35 | F | 131 | 52.67±5.08 | 54 | -7.22 | -6.9 | 3.51E-13 | |
| L | yw/w*; +; Elav/p35 | F | 0 | NA | NA | --------- | --------- | --------- | |
| Exp5 Life span assay of two UAS-p35 lines with GS255B driver at 25C | |||||||||
| 8-1 | - | w/Y; 255B/+; + | M | 121 | 62.33±18.12 | 68 | --------- | --------- | --------- |
| L | w/Y; 255B/+; + | M | 119 | 62.57±16.22 | 68 | 0.39 | 0 | 0.478 | |
| L1-10 | w/Y; 255B/+; + | M | 120 | 66.02±19.38 | 72 | 5.91 | 5.88 | 7.82E-04 | |
| - | w/w; 255B/+; + | F | 123 | 75.95±9.37 | 78 | --------- | --------- | --------- | |
| L | w/w; 255B/+; + | F | 124 | 69.02±12.88 | 74 | -9.13 | -5.13 | 7.69E-07 | |
| L1-10 | w/w; 255B/+; + | F | 124 | 78.18±9.17 | 80 | 2.93 | 2.56 | 7.84E-04 | |
| 10-1 | - | w/Y; 255B/p35; + | M | 111 | 56.32±25.51 | 66 | --------- | --------- | --------- |
| L | w/Y; 255B/p35; + | M | 4 | 16±21.6 | 7 | -71.59 | -89.39 | 6.47E-05 | |
| L1-10 | w/Y; 255B/p35; + | M | 117 | 58.56±17.95 | 62 | 3.98 | -6.06 | 0.528 | |
| - | w/w*; 255B/p35; + | F | 119 | 68.47±13.26 | 72 | --------- | --------- | --------- | |
| L | w/w*; 255B/p35; + | F | 30 | 27.47±16.58 | 24 | -59.89 | -66.67 | 0 | |
| L1-10 | w/w*; 255B/p35; + | F | 124 | 64.5±16.45 | 70 | -5.8 | -2.78 | 0.757 | |
| 11-1 | - | w/Y; 255B/+; p35/+ | M | 117 | 66.15±9.97 | 68 | --------- | --------- | --------- |
| L | w/Y; 255B/+; p35/+ | M | 1 | 14±NA | 14 | -78.84 | -79.41 | 3.38E-14 | |
| L1-10 | w/Y; 255B/+; p35/+ | M | 123 | 64.98±15.73 | 70 | -1.78 | 2.94 | 0.099 | |
| - | w/w*; 255B/+; p35/+ | F | 123 | 74.41±5.98 | 76 | --------- | --------- | --------- | |
| L | w/w*; 255B/+; p35/+ | F | 0 | NA | NA | --------- | --------- | --------- | |
| L1-10 | w/w*; 255B/+; p35/+ | F | 123 | 74.37±11.95 | 78 | -0.04 | 2.63 | 0.003 | |
| Exp6 Life span assay of two UAS-p35 lines with Elav driver at 25C | |||||||||
| 8-5 | - | yw/Y; +/+; Elav/+ | M | 108 | 61.69±17.95 | 67 | --------- | --------- | --------- |
| L1-10 | yw/Y; +/+; Elav/+ | M | 115 | 54.17±15.55 | 58 | -12.18 | -13.43 | 1.80E-08 | |
| - | yw/w; +/+; Elav/+ | F | 120 | 57.42±14.79 | 64 | --------- | --------- | --------- | |
| L1-10 | yw/w; +/+; Elav/+ | F | 117 | 56.41±10.82 | 58 | -1.75 | -9.38 | 0.004 | |
| 10-5 | - | yw/Y; p35/+; Elav/+ | M | 121 | 46.6±7.2 | 46 | --------- | --------- | --------- |
| L1-10 | yw/Y; p35/+; Elav/+ | M | 115 | 37.81±9.05 | 38 | -18.86 | -17.39 | 7.06E-14 | |
| - | yw/w*; p35/+; Elav/+ | F | 123 | 50.63±15.32 | 54 | --------- | --------- | --------- | |
| L1-10 | yw/w*; p35/+; Elav/+ | F | 121 | 49.19±12.16 | 50 | -2.85 | -7.41 | 0.035 | |
| 11-5 | - | yw/Y; +; Elav/p35 | M | 120 | 54.32±13.04 | 56 | --------- | --------- | --------- |
| L1-10 | yw/Y; +; Elav/p35 | M | 111 | 52.31±10.98 | 52 | -3.7 | -7.14 | 0.037 | |
| - | yw/w*; +; Elav/p35 | F | 123 | 52.7±13.97 | 54 | --------- | --------- | --------- | |
| L1-10 | yw/w*; +; Elav/p35 | F | 118 | 56.63±10.73 | 58 | 7.45 | 7.41 | 0.091 | |