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. 2009 Mar 2;1(3):316–327. doi: 10.18632/aging.100028

Figure 3. Effects of RNAi-mediated silencing of survivin and aurora B on S10P histone H3 and SiHa cell phenotype.

Figure 3.

(A) Survivin, aurora B and S10P histone H3 protein levels 48h post-transfection. (B) Phase contrast images of SiHa cells as indicated. (C) Cell cycle distribution at 0, 24, 48 and 72h post-transfection with indicated siRNAs. (D) Induction of polyploidy in SiHa cells following survivin depletion indicated by percentage of >G2 cells and appearance of multinuclear cells.