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. Author manuscript; available in PMC: 2010 Jan 30.
Published in final edited form as: Oncogene. 2009 Jun 1;28(30):2745–2755. doi: 10.1038/onc.2009.130

Figure 6. IL-6 depletion reduces the migration and invasion-promoting effect of ASCs.

Figure 6

(A) IL-6 was removed from ASC-conditioned medium by incubation with a mouse monoclonal IL-6 specific antibody. An isomeric IgG was used as control antibody. The Boyden-chamber migration assay was conducted as shown in the previous figures. (B) Matrigel-based invasion assay of MDA-MB-231 cells using control or IL-6-depleted ASC-conditioned medium. Experiments were carried out in triplicate and repeated three times. Columns were normalized to Control Medium + IgG.