Table 2.
Demographic and clinical characteristics of a national sample of patients whose specimens yielded an adenovirus type 3 (HAdV3). Patients were either recent transplant recipients or <7yrs of age. Each patient contributed only 1 positive adenovirus specimen per unique clinical event.
| Adenovirus types with column percentages |
||||||
|---|---|---|---|---|---|---|
| Variables | Total | HAdV3a2 (n=134) | HAdV3a17 (n=17) | HAdV3a50 (n=102) | HAdV3a51 (n=74) | Other HAdV3a (n=46) |
| Age group** | ||||||
| < 7 years old | 371 | 134 (100) | 17 (100) | 102 (100) | 74 (100) | 44 (95.7) |
| ≥ 7 years old | 2 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (4.3) |
| Immunocompromised** | ||||||
| Cancer | 2 | 1 (0.7) | 0 (0) | 0 (0) | 0 (0) | 1 (2.2) |
| Cancer and transplant | 4 | 0 (0) | 0 (0) | 1 (1) | 0 (0) | 3 (6.5) |
| Nothing reported | 353 | 123 (91.8) | 15 (88.2) | 100 (98) | 74 (100) | 41 (89.1) |
| Transplant | 14 | 10 (7.5) | 2 (11.8) | 1 (1) | 0 (0) | 1 (2.2) |
| Cancer types** | ||||||
| None reported | 367 | 133 (99.3) | 17 (100) | 101 (99) | 74 (100) | 42 (91.3) |
| Lymphatic and hematopoietic tissue | 5 | 1 (0.7) | 0 (0) | 1 (1) | 0 (0) | 3 (6.5) |
| Respiratory or intrathoracic organs | 1 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (2.2) |
| Transplant types** | ||||||
| None reported | 367 | 133 (99.3) | 17 (100) | 101 (99) | 74 (100) | 42 (91.3) |
| Bone marrow | 4 | 0 (0) | 0 (0) | 1 (1) | 0 (0) | 3 (6.5) |
| Heart | 1 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (2.2) |
| Kidney | 1 | 1 (0.7) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Upper respiratory tract infection** | (0) | (0) | (0) | (0) | (0) | |
| Yes | 222 | 63 (47) | 9 (52.9) | 51 (50) | 71 (95.9) | 28 (60.9) |
| Not reported | 151 | 71 (53) | 8 (47.1) | 51 (50) | 3 (4.1) | 18 (39.1) |
| Conjunctivitis** | ||||||
| Yes | 51 | 13 (9.7) | 2 (11.8) | 10 (9.8) | 16 (21.6) | 10 (21.7) |
| Not reported | 322 | 121 (90.3) | 15 (88.2) | 92 (90.2) | 58 (78.4) | 36 (78.3) |
| Days in the hospital**† | ||||||
| Missing | 17 | 11 (8.2) | 3 (17.6) | 3 (2.9) | 0 (0) | 0 (0) |
| No | 220 | 68 (50.7) | 7 (41.2) | 59 (57.8) | 61 (82.4) | 25 (54.3) |
| Yes, 0–2 days | 67 | 29 (21.6) | 3 (17.6) | 24 (23.5) | 5 (6.8) | 6 (13) |
| Yes, 3–385 days | 68 | 26 (19.4) | 4 (23.5) | 15 (14.7) | 8 (10.8) | 15 (32.6) |
| Yes, number of days unknown | 1 | 0 (0) | 0 (0) | 1 (1) | 0 (0) | 0 (0) |
a
“Other HAdV3” includes two patients with a rare HAdV3 variant type (3a, 3a11) and 44 subjects with coinfections. Coinfections are mixed infections with more than one adenovirus type based on REA banding profiles.
**
Statistically significant with chi-squared test at 5% significance level
†
Missing and “Yes, number of days unknown” not included in the statistical test.