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Non-smad TGF-β signaling is required for in vivo collagen III accumulation. Representative immunofluorescence sections of control and UUO kidneys stained with anti-collagen III. The bar graph displays quantification of immunoreactive renal interstitial collagen III; n = 6 each. *P < 0.05 vs. control. **P < 0.05 vs. 50 mg/kg imatinib or 1.5 mg/kg rapamycin.
