Fig. 2.

Cln7^−/− mice failed to thrive. Cln7^+/+ (WT), Cln7^+/− (Het), and Cln7^−/− (KO) mice were weighed on a daily basis from birth to 8 days (A). The length of the mice was measured at the same time (B). The length of mouse was determined by measuring the distance from the top of the head to its tail using a piece of thread. At least 6 mice for each group were included in the measurements. Cln7^−/− mice showed similar weight and size at birth but were not able to grow beyond 5 days. Each data point is presented as means ± SE. *Value is significantly different from the controls (P < 0.05).