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Measurements of fractional excretion (FE) of electrolytes. FE of Na+ (A), Cl− (B), or K+ (C) was measured in 7-day-old Cln7+/+ (WT) and Cln7−/− (KO) mice. Each data point represents at least 7 samples and is presented as mean ± SE. Plasma Na+ (D), Cl− (E), or K+ (F) was measured in 7-day-old Cln7+/+ (WT) and Cln7−/− (KO) mice. Each data point represents at least 10 samples and is presented as mean ± SE. *Significantly different from the WT control (P < 0.05).
