Table 2.
Effects of HC diet on endothelial gene expression
| Upregulated with HC diet |
Downregulated with HC diet |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gene symbol | Gene identification | Confidence* | Gene symbol | Gene identification | Confidence* | |||||
| Atherosusceptible regions | ||||||||||
| ABCA1 | ATP-binding cassette, subfamily A, member 1 | 0.96 | NOV | Nephroblastoma overexpressed | 0.75 | |||||
| APOE | Apoliporotein E | 0.90 | SERPINI1 | Serpin peptidase inhibitor 1 | 0.75 | |||||
| LGALS3 | Galectin 3 | 0.80 | ||||||||
| SPARC | Acidic cysteine-rich secreted protein | 0.75 | ||||||||
| Atheroprotected regions | ||||||||||
| ABCA1 | ATP-binding cassette, subfamily A, member 1 | 0.99 | FNDC1 | Fibronectin type III domain containing 1 | 0.80 | |||||
| CYBB | NADPH oxidase heavy chain subunit | 0.87 | CYBRD1 | Cytochrome b reductase 1 | 0.80 | |||||
| PLTP | Plasma phospholipid transfer protein | 0.87 | ABLIM3 | Actin binding LIM protein family member 1 | 0.80 | |||||
| FOLR1 | Folate receptor 1 | 0.81 | ||||||||
| GLRX | Glutaredoxin | 0.81 | ||||||||
| CSK | C-SRC kinase | 0.77 | ||||||||
| CYBA | NADPH oxidase light chain subunit | 0.77 | ||||||||
| MAN2B1 | Mannosidase, α, class 2B, member 1 | 0.77 | ||||||||
| RNF128 | Ring finger protein 128 | 0.77 | ||||||||
| SCD | Stearoyl-CoA desaturase | 0.77 | ||||||||
| YKT6 | YKT6 v-SNARE protein | 0.77 | ||||||||
*
Estimated confidence based on PaGE permutation algorithm. 1.0 indicates 100% confidence that the gene is differentially expressed.