Table 5.
Proteins with similar changes in PC and GSK Inhib VIII hearts
| Spot No. | Name | Accession No. | Calc MW | Obs MW | Calc pI | Obs pI | Function | Effect in PC | Effect in GSK Inhib VIII |
|---|---|---|---|---|---|---|---|---|---|
| 29, 67 | (P56391) Cytochrome-c oxidase subunit VIb isoform 1 (COX VIb-1). | CX6B1_MOUSE | 10,293 | 10,000 | 8.91 | 8.50, 8.15 | Ox Phos | 110.50% higher | 146.10% higher |
| 31, 69 | (P56391) Cytochrome-c oxidase subunit VIb isoform 1 (COX VIb-1) | CX6B1_MOUSE | 10,293 | 10,000 | 8.91 | 9.20, 9.10 | Ox Phos | 105.70% higher | 266.91% higher |
| 30, 68 | (P62898) Cytochrome c, somatic | NDUA2_MOUSE | 11,023 | 11,000 | 9.61 | 9.15, 9.00 | Ox Phos | 10.37% lower | 58.09% lower |
| 27, 65 | (P97450) ATP synthase-coupling factor 6, mitochondrial precursor | ATP5J_MOUSE | 12,489 | 10,000 | 5.40 | 5.15, 5.15 | Ox Phos | 14.20% higher | 25.90% higher |
| 28, 66 | (P97450) ATP synthase-coupling factor 6, mitochondrial precursor | ATP5J_MOUSE | 12,489 | 10,000 | 5.40 | 5.47, 5.40 | Ox Phos | 16.90% higher | 35.00% higher |
| 25, 64 | (P11240) Cytochrome-c oxidase subunit 5A, mitochondrial precursor | COX5A_MOUSE | 16347 | 15,000 | 5.01 | 5.15, 5.05 | Ox Phos | 13.20% higher | 20.40% higher |
| 26, 63 | (P99028) Cytochrome b-c1 complex subunit 6, mitochondrial precursor | QCR6_MOUSE | 10713 | 11,000 | 4.84 | 5.15, 5.00 | Ox Phos | 15.50% higher | 24.70% higher |
Spot numbers (1st no. PC, 2nd no. GSK Inhib VIII), accession numbers (SwissProt/Uniprot database), calculated and observed MW, calculated and observed pI (1st no. PC, 2nd no. GSK Inhib VIII), and protein function are shown. The calculated pIs shown are for the processed clipped proteins. Data are expressed as % change in PC or GSK Inhib VIII relative to Con.