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. 2003 Nov 1;17(21):2688–2697. doi: 10.1101/gad.1140003

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Copyright © 2003, Cold Spring Harbor Laboratory Press

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Figure 1. — The L box, a highly conserved sequence and structural domain, is present in the 5′-UTRs of Gram-positive and Gram-negative bacterial mRNAs that are related to lysine metabolism. Conserved portions of the L-box sequence and secondary structure were identified by alignment of 32 representative mRNAs as noted. Base-pairing potential representing P1-P5 are individually colored. Nucleotides in red are conserved in >80% of the examples. The asterisk identifies the representative (B. subtilis lysC 5′-UTR) that was examined in this study. Gene names are as annotated in GenBank or were derived by protein sequence similarity. Organism abbreviations are as follows: (BA) Bacillus anthracis; (BH) Bacillus halodurans; (BS) Bacillus subtilis; (BX) Bacillus sp.; (CA) Clostridium acetobutylicum; (CP) Clostridium perfringens; (EC) Escherichia coli; (HI) Haemophilus influenzae; (OI) Oceanobacillus iheyensis; (PM) Pasteurella multocida; (SA) Staphylococcus aureus; (SE) Staphylococcus epidermidis; (SF) Shigella flexneri; (SO) Shewanella oneidensis; (TM) Thermatoga maritima; (TT) Thermoanaerobacter tengcongensis; (VC) Vibrio cholerae; (VV) Vibrio vulnificus.