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. 2009 Nov 11;298(1):R198–R210. doi: 10.1152/ajpregu.00325.2009

Fig. 1.

Fig. 1.

Skeletal muscle IL-6 mRNA and IL-6 promoter luciferase levels are increased by exercise. IL-6 mRNA levels in the tibialis anterior (TA) from unexercised wild-type C57 mice and from mice run to exhaustion on a treadmill (A), and from unexercised control wild-type C57 mice and mice allowed access to a cage wheel for 3 days. Data represent means ± SE for n = 4 animals for each group. B: IL-6 mRNA levels in the TA in unexercised mice and in mice following 3 days of voluntary wheel running. Data are expressed as means ± SE for n = 8 animals for each group. C: Firefly luciferase levels were quantified from IL-6-luc transgenic mice following a single bout of treadmill exercise Data represent mean ± SE for n = 4 animals for each group. D: both voluntary and treadmill exercise resulted in a significant increase in TA IL-6 mRNA and luciferase levels. Data are expressed as means ± SE for n = 4 animals for each group. *Significantly different from unexercised, P < 0.05.