Fig. 6.

Effect of intracerebroventricular injection of an oxytocin antagonist, [d(CH₂)₅¹,Tyr(Me)²,Orn⁸]-oxytocin (100 ng) on gastric motility following chronic repeated restraint stress. At day 1, restraint stress significantly attenuated gastric motility, which was partially restored at day 3 and completely restored at day 5. The administration of an oxytocin antagonist significantly antagonized the restored gastric motility following chronic stress loading. MI was reduced to 51.6 ± 1.9% (n = 5; P < 0.05) of basal by an oxytocin antagonist.