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. 2009 Nov 4;298(1):R157–R165. doi: 10.1152/ajpregu.00328.2009

Fig. 7.

Fig. 7.

Effect of acute and chronic repeated restraint stress on CRF mRNA expression (A) and oxytocin mRNA expression (B) in the paraventricular nucleus (PVN) and supraoptic nucleus (SON). CRF mRNA expression showed a significant increase in response to acute stress. The increment of CRF mRNA was much less at the PVN following chronic stress, compared with that of acutely stressed mice. Oxytocin mRNA expression at the PVN and SON showed a more pronounced increase following chronic stress, compared with that of acutely stressed rats. The mRNA expression was standardized with the ratio of internal control, β actin (n = 6; *P < 0.05, **P < 0.01 compared with controls).