Table 1.
Representative sequence motifs enriched in HP1 and HP1c binding sites
| HP1
|
HP1c
|
|||
|---|---|---|---|---|
| Motif | P-value | Motif | P-value | |
| AAAAAT | <10-12 | AAATAAA | <10-12 | |
| AAAAATT | <10-12 | TTTTTT | <10-12 | |
| AAAATT | <10-12 | ATTTTT | <10-12 | |
| AATTTTT | <10-12 | TATTTTT | <10-12 | |
| AAAAT | <10-12 | TTTTTA | <10-12 | |
| ATTTTT | <10-12 | — | ||
| AAATTT | <10-12 | TACATA | <10-12 | |
| AAAATTT | <10-12 | ATACATA | <10-12 | |
| TTTTTA | <10-12 | ATATGTA | 2 × 10-12 | |
| TAAAA | <10-12 | TACATAT | 7 × 10-10 | |
| TAAAAA | <10-12 | TATGTA | 1 × 10-9 | |
| AATTTT | <10-12 | ACATATG | 6 × 10-9 | |
| — | — | |||
| AT-stretches | AT-stretches + (at)ACATA(tgt) | |||
No motifs were positively correlated with Su(var)3-9 binding. Motifs were obtained by applying the REDUCE algorithm (Bussemaker et al. 2001; see Materials and Methods). See Supplemental Material for a complete list of motifs and associated P-values.