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cKO mice show reduced hippocampal BDNF levels. A, Quantification of BDNF protein levels (Mean ± SEM, pg/mg). 5-13 animals/group. *, P < 0.05; **, P < 0.01. B, Levels of hippocampal BDNF after sub-grouping the EE groups into low-activity and high-activity groups. *, P < 0.05; **, P < 0.01.
