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. 2009 Dec 21;206(13):3115–3130. doi: 10.1084/jem.20091756

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© 2009 Ginhoux et al.

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Figure 7. — Pre-DCs are present in nonlymphoid tissues. (A) Dot plots show the relative numbers of CD45⁺MHCII⁺CD11c⁻Flt3^hiSIRP-α⁻ pre-DCs among hematopoietic cells in the lung, kidney, liver, and spleen. (B) Bar graph shows the relative numbers of pre-DCs in indicated organs of Flt3L^+/+ (WT, white) and Flt3L^−/− (black) mice. One representative experiment of three (A) and two (B) independent experiments is shown (n = 2). (C) CD45.2 and CD45.1 C57BL/6 mice were surgically joined for 55 d. Graphs show the percentage of parabiont-derived T cells, B cells, and pre-DCs in the blood and the percentage of parabiont-derived pre-DCs in the lung, kidney, liver, and spleen 55 d after parabiosis was established. The bar graphs summarize two independent experiments with more than three mice in total. Error bars represent the mean ± SEM.