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. 2009 Dec 21;206(13):2869–2877. doi: 10.1084/jem.20090845

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© 2009 Conrad et al.

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Figure 3. — Single or chronic A. lwoffii F78 exposure induces local and systemic innate immune responses. All animals used were age equivalent to breeding mothers. White bars represent PBS control exposure, and black bars represent A. lwoffii F78 exposure. (A–C) Single-exposure kinetic. Results represent one out of two independently performed experiments with similar outcomes (n ≥ 7 per group). (A) Differential leukocyte numbers in the BAL. (B) Local concentration of proinflammatory cytokines in BAL fluid. (C) Serum IL-6 concentration. (D and E) Chronic exposure three times per week for 5 wk. Results represent one out of two independently performed experiments with similar outcomes (n = 4 per group). (D) Differential leukocyte numbers in BAL. (E) Local concentration of proinflammatory cytokines in BAL fluid after chronic exposure to A. lwoffii F78. Means ± SEM are shown. *, P < 0.05; **, P < 0.01; ***, P < 0.001. nd, not detectable.