Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Dec 21;206(13):3101–3114. doi: 10.1084/jem.20091925

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2009 Schulz et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 7. — CX3CR1⁺ LPCs display weak ALDH activity and fail to efficiently induce CCR9 on responding CD8 T cells. (A) Aldh1a2 expression of sorted CD103⁺ DC, CX3CR1^int LPC, and CX3CR1^high LPC was assessed by real-time PCR. The mean (horizontal lines) was obtained from three separate experiments using pooled cells from five to eight mice per experiment. Results were obtained with an unpaired Student's t test. **, P < 0.01; ***, P < 0.001. (B and C) ALDH activity on sorted CD103⁺ DC and MHCII⁺F4/80⁺CD11b⁺ LPC with or without addition of inhibitor. (B and C) Representative stainings (B) and mean (C; horizontal lines) of five individual mice (symbols). Results were obtained with a paired Student's t test. **, P < 0.01. (D) CFSE-labeled OT-I cells were co-cultured with peptide-loaded CD103⁺ DC, CX3CR1^high LPC, or CX3CR1^int LPC at a ratio of 2:1 for 3.5 d and expression of CCR9 on responding OT-I cells was analyzed. Results are representative of two experiments.