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. Author manuscript; available in PMC: 2010 Jan 13.
Published in final edited form as: Learn Mem. 2002 Sep–Oct;9(5):224–237. doi: 10.1101/lm.51202

Figure 4.

Figure 4

Hippocampal BDNF is required for the formation of both short- and long-term memory. (A) Median (interquartile range) latency to step down from the platform of the inhibitory avoidance box in the test session 1.5 h after training. Histograms represent latency scores for animals receiving bilateral CA1 infusions of saline, BDNF (0.25 μg/side), or a function-blocking anti-BDNF antibody (0.5 μg/side), 15 min prior to, immediately before, or 1 h following avoidance training. (B) Median (interquartile range) latency to step down from the platform of the inhibitory avoidance box in the test session 24 h after training. Histograms represent latency scores for animals receiving bilateral CA1 infusions of saline, BDNF (0.25 μg/side), or anti-BDNF antibody (0.5 μg/side), 15 min prior to, immediately before, or 1, 4, or 6 h following avoidance training. Adapted from Alonso et al. (2002).