Table 4.

Haplotypes of the MTHFR gene showing significant or nearly significant association with ANM

Haplotype	SNP1	SNP2	SNP3	SNP4	SNP5	SNP6	Haplotype frequency	R2	β	P
A			T	G			0.540	0.017	−0.86	0.09
B				G	G	T	0.049	0.024	−2.67	0.04
C		A	T	G			0.268	0.018	−0.95	0.08
D			T	G	G	T	0.046	0.024	−2.65	0.04
E			T	G	A	G	0.150	0.023	− 1.17	0.05
F		A	T	G	A	G	0.147	0.020	− 1.09	0.06
G	C	A	T	G	A	G	0.147	0.020	−1.09	0.06