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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2010 Jan;88(1):25–34. doi: 10.1002/bdra.20623

Table 1.

Developmental outcomes following in utero exposure to 20 mg/kg As (V) a

Dose No. of litters (N) No. of implants (N) No. of resorptions (%) b No. of birth defectsd (%) c No. of live births (N)
0 (vehicle) 12 108 3 (2.8) 1 (0.95) 102
20 mg/kg 11 100 15 (15)* 8 (10.2)* 77
a

Dams were injected intraperitonially on gd 7 and 8 and the fetuses examined on gd 17.5.

b

Percent of implants.

c

Percent from the total number of live born fetuses

d

Birth defects include NTDs, orofacial abnormalities and gastroschisis.

*

Significantly different when compared to vehicle treated control animals (p< 0.05).