Fig. 3.

Deduced amino acid sequence of the ORF-P-encoded, RDP1 protein. a The RDP1 gene encodes a protein of 410 amino acids. The C3HC4 RING zinc finger domain is shown in bold. b Comparison of the conventional C3HC4 RING zinc finger motif (upper) with that present in RDP1 (lower). C and H denote conserved cysteine and histidine residues, respectively, and X represents generic amino acids. The non-canonical residues are highlighted in red. Note that the spacing between the fourth and fifth cysteine is one amino acid in RDP1 in contrast to two amino acids in the conventional C3HC4 RING zinc finger