Table 3.

Multivariate adjusted* odds ratios by p53 status relative to polyp-free controls.

	No p53 protein overexpression (-)	p53 protein overexpression (+)	Case/Case comparison
(A) Associations using all cases (adenomas, CIS, IM)
Duration of Cigarette Smoking
Nonsmoker	1.0	1.0
< 15 years	1.5 (0.7–3.0)	2.1 (0.7–6.4)	1.5 (0.4–4.9)
15 – 29 years	1.0 (0.5–1.8)	0.9 (0.3–2.8)	0.9 (0.3–3.1)
30+ years	1.8 (1.1–2.9)	1.0 (0.4–2.6)	0.6 (0.2–1.5)
Pipes or cigars
Never	1.0	1.0
Ever	0.6 (0.3–1.2)	1.3 (0.4–4.0)	2.1 (0.7–6.9)
Beer Consumption
Nondrinker	1.0	1.0
1–7 bottles/week	1.5 (0.9–2.5)	0.4 (0.1–1.9)	0.3 (0.1–1.4)
8+ bottles/week	1.6 (0.7–3.7)	4.0 (1.3–12.0)	2.5 (0.7–8.1)
Body Size
Body mass index (kg/m2)
< 22.5	1.0	1.0
22.5 – <25.5	1.2 (0.7–2.1)	1.2(0.4–3.5)	1.1 (0.4–3.3)
25.5+	1.8 (1.0–3.1)	1.5 (0.6–4.2)	0.9 (0.3–2.5)
(B) Associations using all only cases with advanced adenomas (CIS and IM)
Duration of Cigarette Smoking
Nonsmoker	1.0	1.0
< 15 years	1.1 (0.4–2.8)	2.7 (0.8–9.6)	2.5(0.6–11.7)
15 – 29 years	0.7 (0.3–1.7)	0.7 (0.2–2.7)	1.0 (0.2–4.5)
30+ years	1.9 (1.0–3.5)	0.9 (0.3–2.8)	0.5 (0.2–1.7)
Pipes or cigars
Never	1.0	1.0
Ever	0.5 (0.2–1.2)	1.5 (0.4–5.5)	2.9(0.6–12.9)
Beer Consumption
Nondrinker	1.0	1.0
1–7 bottles/week	0.9 (0.4–2.0)	0.3 (0.04–2.4)	0.3(0.04–2.9)
8+ bottles/week	1.4 (0.5–3.8)	4.1 (1.2–14.4)	3.0(0.7–13.2)
Body Size
Body mass index (kg/m2)
< 22.5	1.0	1.0
22.5 – <25.5	0.8 (0.4–1.7)	1.4(0.4–4.8)	1.7 (0.4–6.7)
25.5+	1.3 (0.7–2.6)	2.2 (0.7–7.0)	1.7 (0.5–6.1)

*age, age², gender, race, and the other variables listed in the table.