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. 2009 Nov 23;206(12):2603–2611. doi: 10.1084/jem.20091707

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© 2009 Krijger et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 1. — Current model: pathways of SHM downstream of AID. The three pathways: (a) replication across U, (b) Ung2-dependent SHM, and (c) Msh2-dependent SHM. Known and unknown (?) polymerases involved in the generation of specific mutations are indicated. TS, transitions; TV, transversions.