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. 2009 Nov 23;206(12):2603–2611. doi: 10.1084/jem.20091707

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© 2009 Krijger et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 3. — Absolute frequency mutations grouped into G/C transitions, G/C transversions, and A/T mutations. Absolute mutation frequency of A/T mutations, G/C transitions (TS), and G/C transversions (TV). Values are expressed as the percentage of total sequenced base pairs from mutated clones. The contribution of single nucleotide substitutions is revealed in Fig. S2. Asterisks indicate significant changes compared with WT (χ² test; all significant changes had a p-value <10⁻⁵, and nonsignificant changes had a p-value >0.1). The number of mice analyzed is indicated in Table I.