Fig 2 Interaction tests on logistic regression base model, 36 months intention to treat scenario. Each panel shows summary of 10 separate interaction analyses, testing statistical significance of each treatment by covariate interaction term added to base model. Coefficients differing significantly from 1.0 indicate presence of interaction (non-proportional hazards) between covariate and treatment; coefficients below 1.0 indicate greater treatment response (lower risk of fracture), and coefficients above 1.0 indicate smaller treatment response (higher risk of fracture). HRT=hormone replacement therapy