Effects of the adenosine A2A antagonist KW6002 in combination with 0.1 mg/kg haloperidol. (A) Mean (±S.E.M.) number of lever presses after treatment with vehicle or haloperidol plus various doses of KW6002 are shown. (B) Mean (±S.E.M.) intake of lab chow (in grams) after treatment with vehicle or haloperidol plus various doses of KW6002 are shown. Veh/Veh (vehicle plus vehicle), HP/Veh (0.1 mg/kg haloperidol plus vehicle), HP/KW 0.125 (0.1 mg/kg haloperidol plus 0.125 mg/kg KW6002), HP/KW 0.25 (0.1 mg/kg haloperidol plus 0.125 mg/kg KW6002), HP/KW 0.5 (0.1 mg/kg haloperidol plus 0.5 mg/kg KW6002). #p < 0.01, haloperidol different from vehicle/vehicle, planned comparison; *p < 0.05, different from vehicle plus haloperidol, planned comparison.