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. Author manuscript; available in PMC: 2010 Jan 14.
Published in final edited form as: Exp Neurol. 2009 May 5;218(1):162–167. doi: 10.1016/j.expneurol.2009.04.025

Fig. 5.

Fig. 5

Brain-to-blood efflux of PrPc after icv injection. Half-time clearance from brain was 15.7 min. Inset shows that inclusion of unlabeled PrPc in the icv injection increased retention of radioactively labeled PrPc by brain, demonstrating a saturable component to the brain-to-blood transport of PrPc.