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. Author manuscript; available in PMC: 2010 Jan 14.
Published in final edited form as: Exp Neurol. 2009 May 5;218(1):162–167. doi: 10.1016/j.expneurol.2009.04.025

Table 3.

Inhibition of I-PrPc uptake by 10 μg/mouse unlabeled PrPc.

CNS region I-PrPc only +PrPc
Whole brain 31.2 ± 2.0 22.3 ± 0.8**
Olfactory bulb 49.5 ± 1.2 34.8 ± 3.6**
Frontal cortex 18.4 ± 2.0 16.1 ± 2.0
Parietal cortex 22.2 ± 1.8 17.7 ± 1.4
Occipital cortex 49.3 ± 9.1 26.8 ± 4.3*
Hypothalamus 97.4 ± 6.6 105 ± 13.1
Thalamus 65.5 ± 10.2 32.8 ± 5.8*
Striatum 74.8 ± 14.9 32.9 ± 8.2*
Hippocampus 30.2 ± 1.8 29.4 ± 2.6
Cerebellum 25.6 ± 2.3 20.2 ± 1.2
Midbrain 34.1 ± 2.9 22.8 ± 1.7**
Pons medulla 24.2 ± 0.8 21.8 ± 1.5
Cervical spinal cord 65.6 ± 3.0 47.5 ± 4.6*
Thoracic spinal cord 24.6 ± 2.6 23.5 ± 2.1
Lumbar spinal cord 295 ± 62 73.5 ± 20.3*

Means are shown with their SE (n = 4–6/group). Tissue/serum ratios expressed in ml/g.

*

p <0.05 and

**

p <0.01 when compared to I-PrPc. Only for the respective region.