Fig. 1.
Comparative effects of BPA and estradiol on intestinal permeability in OVX rats. (A) Dose effect of BPA (0.5 μg to 5 mg/kg/d for 15 d by mouth) on colonic paracellular permeability (six to eight rats per group; P < 0.05, one-way ANOVA). (B) Effects of 15-d treatment with corn oil (control), BPA NOAEL or TDI, or EB with or without ICI 182.780 (ICI) on paracellular dextran flux (5–13 rats per group). **P < 0.01 vs. controls; ns, not significant on one-way ANOVA. Bars are means ± SEM of triplicate measurements.